Scientists found a way to help ageing guts heal themselves: Study

Summary

Researchers have found that CAR T-cell therapy can help aging intestines heal themselves by targeting senescent cells, improving gut regeneration, reducing inflammation, and protecting against radiation damage in mice.

Key Points
  • Researchers used CAR T-cell therapy to remove senescent cells in mice intestines, boosting gut regeneration and nutrient absorption.
  • The treatment reduced inflammation and helped the epithelial lining of intestines heal faster in both young and old mice.
  • CAR T-cell therapy protected mice intestines from radiation damage, with benefits lasting up to a year.
  • Early evidence suggests the therapy could improve gut health in older adults and cancer patients by promoting intestinal repair in human cells.
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