Scientists reverse Alzheimer’s in mice and restore memory: Study

Summary

Scientists have found that restoring the brain's energy molecule NAD+ can reverse Alzheimer's disease and restore memory in mice, offering new hope for treatment.

Key Points
  • Restoring NAD+ balance in mouse models reversed Alzheimer’s brain pathology and cognitive deficits.
  • The treatment used was a pharmacologic compound called P7C3-A20 developed to maintain NAD+ balance.
  • Alzheimer’s brains exhibit severe drops in NAD+ levels, hindering cellular function and survival.
  • Research suggests Alzheimer’s damage may be reversible, challenging the belief that the disease is permanent.
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