The Nobel Prize in medicine goes to 3 scientists for key immune system discoveries

Summary

Three scientists won the 2025 Nobel Prize in medicine for discovering regulatory T cells that regulate the immune system and their role in autoimmune diseases and treatments.

Key Points
  • Mary E. Brunkow, Fred Ramsdell, and Dr. Shimon Sakaguchi won the 2025 Nobel Prize in medicine for discoveries about immune system regulation.
  • They identified regulatory T cells and the Foxp3 gene's role in peripheral immune tolerance to prevent autoimmune diseases.
  • Their research advances understanding of diseases like Type 1 diabetes, rheumatoid arthritis, and lupus, and may lead to better therapies.
  • The discoveries are foundational for ongoing developments in autoimmune disease treatments, organ transplants, and cancer therapy.
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