Brunkow, Ramsdell and Sakaguchi win Nobel medicine prize for immune discoveries

Summary

American scientists Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi won the 2025 Nobel Prize in Medicine for their discoveries in immune system regulation, which may lead to new treatments for autoimmune diseases and cancer.

Key Points
  • American scientists Mary Brunkow and Fred Ramsdell, along with Japanese scientist Shimon Sakaguchi, won the 2025 Nobel Prize in Physiology or Medicine.
  • They were awarded for their discoveries related to peripheral immune tolerance and regulatory T cells that control immune system activity.
  • Their work has paved the way for new treatments targeting autoimmune diseases and cancer.
  • The Nobel Prize is awarded by the Karolinska Institute and includes a monetary prize and a gold medal presented by the King of Sweden.
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