Research finds fat may secretly fuel Alzheimer’s
Summary
Research from Houston Methodist reveals that extracellular vesicles from fat tissue may accelerate amyloid-b plaque buildup, linking obesity to Alzheimer’s disease.
Key Points
- Obesity may directly contribute to Alzheimer's disease via extracellular vesicles from fat tissue.
- These vesicles cross the blood-brain barrier and carry harmful signals that accelerate amyloid-b plaque buildup.
- Lipid cargo of vesicles differs between obese and lean individuals, affecting amyloid-b aggregation rates.
- Targeting these vesicles could offer future therapeutic avenues to reduce Alzheimer's risk in obese individuals.
