Scientists uncover cellular “toolkit” to reprogram immune cells for cancer therapy: Study
Summary
Researchers at Lund University have identified genetic toolkits that reprogram ordinary cells into specialized dendritic immune cells, potentially advancing personalized cancer immunotherapy.
Key Points
- Researchers at Lund University identified molecular tools to reprogram ordinary cells into specialized dendritic immune cells.
- Two distinct transcription factor combinations can reprogram cells into conventional type 2 and plasmacytoid dendritic cells.
- Engineered dendritic cells triggered strong immune responses against melanoma and breast cancer in mouse models.
- Findings suggest potential for personalized immunotherapy and applications in autoimmune disease treatment.
