Japan hospital performs first surgery using heart muscle stem cells

Summary

A hospital in Japan has performed the world’s first surgery using sheets of commercially available heart muscle stem cells after the regenerative therapy won conditional approval. The procedure used iPS cell-derived muscle sheets to treat a woman in her 50s, with further trials planned on 75 patients by 2033.

Key Points
  • A hospital in Japan carried out the world’s first surgery using sheets of commercially available heart muscle stem cells.
  • The procedure used iPS cell-derived muscle sheets transplanted into the heart of a woman in her 50s.
  • The therapy had already shown symptom relief in eight trial patients with ischemic heart disease.
  • The team plans to conduct similar operations on 75 patients by 2033 before seeking full authorization.
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