Scientists solve a major roadblock in cancer cell therapy: Study
Summary
Researchers at the University of British Columbia have found a reliable method to produce helper T cells from stem cells, overcoming a key barrier in immune-based cancer therapy and potentially enabling cheaper, scalable off-the-shelf treatments.
Key Points
- Researchers discovered a reliable way to grow helper T cells from stem cells, overcoming a major challenge in immune-based cancer therapy.
- The team identified that precise control of the Notch signaling pathway determines whether stem cells develop into helper or killer T cells.
- Lab-grown helper T cells functioned like genuine human immune cells, showing full maturity and immune receptor diversity.
- This advance opens the door to scalable, affordable off-the-shelf immune cell therapies effective against cancer and other diseases.
